Join us for an Agilent Cell Analysis Virtual Event

A Next Generation Tool Bench for Virology Research

Tuesday,
November 24, 2020

07:30 - 09:30am EST
12:30 - 02:30pm GMT
01:30 - 03:30pm CET

The next generation of vaccines and anti-viral therapies require a new generation of analysis tools.

Research advancing our understanding of host-pathogen and host-immune response to virus infection is critical and timely under the current global pandemic.

Discover Agilent’s new end-to-end solutions for virology disease research, drug discovery and vaccine development, enabling translational researchers and developers to address present and future challenges in global human health and infectious disease.

Register for our Virtual Roadshow, where we will be joined by Dr. Andreas Bergthaler from the Research Center for Molecular Medicine of the Austrian Academy of Sciences and Dr. Alexander Lercher, Postdoctoral Fellow. Rockefeller University, Charlie Rice Lab, New York City, USA. Learn also from Agilent product experts who will showcase relevant product lines and assays, including Seahorse XF technology, xCELLigence RTCA, NovoCyte Flow Cytometry & BioTek Instruments, supported by published application examples from the field.

Meet our presenters

Type I interferon reprograms hepatocyte metabolism to shape pathophysiology during viral hepatitis

Dr. Alexander Lercher did his PhD in the Bergthaler laboratory at CeMM, where he identified the antiviral cytokine type I interferon as key modulator of systemic metabolites by rewiring metabolism during viral infection, which subsequently impacts antiviral immunity and tissue damage.

In 2020, he joined the laboratory of Charles M. Rice at Rockefeller University where he employs holistic approaches towards tissue immunity to unveil mechanisms by which the cellular environment shapes immunological decision points that define short- and long-term immunity towards viral pathogens.

Twitter account: @alex_lercher

Dr. Alexander Lercher.
Postdoctoral Fellow.
Rockefeller University,
Charlie Rice Lab,
New York City, USA.

Exploring uncharted territories of systemic immunometabolism

Dr. Andreas Bergthaler leads an ERC-funded research group at the CeMM Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, Austria. His interests are focused on viral pathogenesis, immunometabolism, inflammation and viral evolution.

Recent studies include new insights into liver immunometabolism (Bhattacharya A et al. Immunity 2015, Lercher A et al. Immunity 2019, Lercher A et al. PLoS Pathogens 2020), infection-associated cachexia (Baazim et al. Nat Immunol 2019), and a review about the intriguing opportunities as well as challenges for studying systemic immunometabolism in the whole organism (Lercher A et al. Immunity 2020).

Lab website: http://www.bergthaler1.at Lab Twitter account: @BergthalerLab

Dr. Andreas Bergthaler,
Principal Investigator,
CeMM of the Austrian Academy of Sciences,
Vienna, Austria

Seahorse XF Reveals Bioenergetic Impact in Virology

Dr. Gebhard joined Agilent as a Product Specialist for Cell Analysis in October 2015. He worked as a researcher/teaching assistant at the Albstadt-Sigmaringen University from 2007-2015 where his main research interest was the influence of solar radiation on the skin and mitochondria. Dr. Gebhard received his Ph.D. in Biology from the University of Konstanz in 2014.

At Agilent Dr Gebhard supports investigators in their cell biology research in Austria, Germany, and Netherlands to better understand central process such as cell activation, differentiation, proliferation, migration, and cell death with life cell metabolism measurements

Dr. Daniel Gebhard,
Product Specialist, Germany, Austria,
Cell Analysis Division, Agilent

Rapid functional evaluation of virus-neutralizing antibodies using multi-parametric live cell analysis

Dr. Silke Schwengberg studied Biology with a focus on cell biology and immunology at the Ruhr-Universität Bochum. She received her PhD from University of Hannover, working at Hannover Medical School on isolation and characterization of human intestinal mast cells. Starting in 1999, she worked for two years at Janssen Pharmaceutical as a scientist in the department of gastrointestinal pharmacology.

In 2001 she moved to then newly founded Cologne Biotech Axiogenesis AG working on development of stem cell-derived cardiomyocytes as well as cell-based test systems. e.g. for cardiotoxicity using the xCELLigence RTCA Cardio instrument. Since 2013 she works as a freelance scientific consultant, among others for ACEA Biosciences and now Agilent.

Dr. Silke Schwengberg
Country Manager Germany,
Austria, Switzerland,
Cell Analysis Division, Agilent

Focus on Virology: Applications to Enable Discovery

Kristen N. Peters Olson, Ph.D. is an Imaging Specialist and Field Applications Scientist for BioTek Instruments in the Greater Boston Area. She received her Ph.D. in Molecular Microbiology and Immunology and Pathobiology from the University of Missouri in 2012. Her dissertation focused on the Yersinia pestis effector protein, YopK, in modulating cell death modality during pneumonic plague. This in vivo infection model focused on the lung immune response to pneumonic plague and was performed in BSL3 conditions at the University of Missouri Laboratory for Infectious Disease Research. In her postdoctoral position at University of Massachusetts Medical School, she studied efferocytosis and its impact on the innate and adaptive immune response in the lung during tuberculosis. To broaden her infectious disease expertise, she accepted a postdoctoral position at the National Emerging Infectious Diseases Laboratories at Boston University, focused on Ebola, Marburg, and Lassa viruses. There, she collaborated with academic colleagues and industry leaders to develop a no-wash diagnostic assay based on SERS technology for the detection of hemorrhagic fever viruses in the field. With the onset of the Zika epidemic, she shifted her focus to Zika virus and developed a novel human placental explant model of infection to understand the cellular tropism, host response, and how the virus causes such severe impact to the developing fetus. This diverse background focusing on host-pathogen interaction in multiple disease models using a variety of assays prepared her for her current position. As an Imaging Specialist for BioTek Instruments, she assists researchers in learning automated imaging technology, developing protocols to best suit their needs, and providing suggestions to improve their research.

Dr. Kristen Olson
Imaging Specialist and Field Applications Scientist
BioTek Instruments, a part of Agilent

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