In this presentation, Julie Eakins, Senior Research Scientist of Cyprotex will discuss a number of in vitro approaches to detect compounds which can result in mitochondrial toxicity. The early detection of compounds which interfere with mitochondrial function is important in the development of safe new drugs. Using a combination of different assays on the flux analyser, it is possible to gain insights into the mechanisms of this toxicity which may aid compound design.
Tune in to learn more about:
- Mitochondrial Toxicity and the importance of identification early in the drug discovery process.
- Use of in vitro screens to improve detection.
- Gaining insights into mechanisms of mitochondrial toxicity.