XF出版物快报 2019年2月

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Aging Research

Drug Synergy Slows Aging and Improves Healthspan through IGF and SREBP Lipid Signaling
Admasu, T. D., Chaithanya Batchu, K., Barardo, D., Ng, L. F., Lam, V. Y. M., Xiao, L., Cazenave-Gassiot, A., Wenk, M. R., Tolwinski, N. S. and Gruber, J.
Dev Cell. 2018 Oct 8, 47(1):67-79 e5.

Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFkappaB
O'Leary, M. F., Wallace, G. R., Davis, E. T., Murphy, D. P., Nicholson, T., Bennett, A. J., Tsintzas, K. and Jones, S. W.
Sci Rep. 2018 Oct 18, 8(1):15360.

Age-dependent changes in intervertebral disc cell mitochondria and bioenergetics
Hartman, R., Patil, P., Tisherman, R., St Croix, C., Niedernhofer, L. J., Robbins, P. D., Ambrosio, F., Van Houten, B., Sowa, G. and Vo, N.
Eur Cell Mater. 2018 Oct 18, 36(171-183.

MiR-34a and stroke: Assessment of non-modifiable biological risk factors in cerebral ischemia
Ren, X., Engler-Chiurazzi, E. B., Russell, A. E., Sarkar, S. N., Rellick, S. L., Lewis, S., Corbin, D., Clapper, J. and Simpkins, J. W.
Neurochem Int. 2018 Oct 23, [epub ahead of print]

Cancer Research

Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer
Eichenlaub, T., Villadsen, R., Freitas, F. C. P., Andrejeva, D., Aldana, B. I., Nguyen, H. T., Petersen, O. W., Gorodkin, J., Herranz, H. and Cohen, S. M.
Curr Biol. 2018 Oct 22, 28(20):3220-3228 e6.

Inhibition of Protein Phosphatase 2A Sensitizes Mucoepidermoid Carcinoma to Chemotherapy via the PI3K-AKT Pathway in Response to Insulin Stimulus
Liu, L., Wang, H., Cui, J., Zhang, Q., Zhang, W., Xu, W., Lu, H., Liu, S., Shen, S., Fang, F., Li, L., Yang, W., Zhuang, Z. and Li, J.
Cell Physiol Biochem. 2018 Oct 3, [epub ahead of print]

Effect of Differences in Metabolic Activity of Melanoma Models on Response to Lonidamine plus Doxorubicin
Nath, K., Roman, J., Nelson, D. S., Guo, L., Lee, S. C., Orlovskiy, S., Muriuki, K., Heitjan, D. F., Pickup, S., Leeper, D. B., Blair, I. A., Putt, M. E. and Glickson, J. D.
Sci Rep. 2018 Oct 2, 8(1):14654.

Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment
Ma, J., Huo, X., Jarpe, M. B., Kavelaars, A. and Heijnen, C. J.
Acta Neuropathol Commun. 2018 Oct 1, 6(1):103.

LDeprenyl exerts cytotoxicity towards acute myeloid leukemia through inhibition of mitochondrial respiration
Ryu, I., Ryu, M. J., Han, J., Kim, S. J., Lee, M. J., Ju, X., Yoo, B. H., Lee, Y. L., Jang, Y., Song, I. C., Chung, W., Oh, E., Heo, J. Y. and Kweon, G. R.
Oncol Rep. 2018 Dec 1, 40(6):3869-3878.

HMGA2 as a functional antagonist of PARP1 inhibitors in tumor cells
Hombach-Klonisch, S., Kalantari, F., Medapati, M. R., Natarajan, S., Krishnan, S. N., Kumar-Kanojia, A., Thanasupawat, T., Begum, F., Xu, F. Y., Hatch, G. M., Los, M. and Klonisch, T.
Mol Oncol. 2019 Feb 1, 13(2):153-170.

Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice
Gorgulu, K., Diakopoulos, K. N., Ai, J., Schoeps, B., Kabacaoglu, D., Karpathaki, A. F., Ciecielski, K. J., Kaya-Aksoy, E., Ruess, D. A., Berninger, A., Kowalska, M., Stevanovic, M., Wormann, S. M., Wartmann, T., Zhao, Y., Halangk, W., Voronina, S., Tepikin, A., Schlitter, A. M., Steiger, K., Artati, A., Adamski, J., Aichler, M., Walch, A., Jastroch, M., Hartleben, G., Mantzoros, C. S., Weichert, W., Schmid, R. M., Herzig, S., Kruger, A., Sainz, B., Jr., Lesina, M. and Algul, H.
Gastroenterology. 2019 Jan 1, 156(1):203-217 e20.

Characterization of the eugenol effects on the bioenergetic profile of SCC-4 human squamous cell carcinoma cell line
Duicu, O., Pavel, I., Borcan, F., Muntean, D., Cheveresan, A., Bratu, E. A., Rusu, L. and Karancsi, O. L.
REV CHIM-BUCHAREST. 2018 Sep 1, 69(2567-2570.

The arginase inhibitor Nomega-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target
Ng, K. P., Manjeri, A., Lee, L. M., Chan, Z. E., Tan, C. Y., Tan, Q. D., Majeed, A., Lee, K. L., Chuah, C., Suda, T. and Ong, S. T.
PLoS One. 2018 Oct 11, 13(10):e0205254.

Mitochondrial enzyme GLUD2 plays a critical role in glioblastoma progression
Franceschi, S., Corsinovi, D., Lessi, F., Tantillo, E., Aretini, P., Menicagli, M., Scopelliti, C., Civita, P., Pasqualetti, F., Naccarato, A. G., Ori, M. and Mazzanti, C. M.
EBioMedicine. 2018 Nov 1, 37(56-67.

beta2-Adrenergic receptor modulates mitochondrial metabolism and disease progression in recurrent/metastatic HPV(+) HNSCC
Lucido, C. T., Callejas-Valera, J. L., Colbert, P. L., Vermeer, D. W., Miskimins, W. K., Spanos, W. C. and Vermeer, P. D.
Oncogenesis. 2018 Oct 8, 7(10):81.

Real-Time Imaging of Mitochondrial ATP Dynamics Reveals the Metabolic Setting of Single Cells
Depaoli, M. R., Karsten, F., Madreiter-Sokolowski, C. T., Klec, C., Gottschalk, B., Bischof, H., Eroglu, E., Waldeck-Weiermair, M., Simmen, T., Graier, W. F. and Malli, R.
Cell Rep. 2018 Oct 9, 25(2):501-512 e3.

High Glucose Induces VEGF-C Expression via the LPA1/3-Akt-ROS-LEDGF Signaling Axis in Human Prostate Cancer PC-3 Cells
Huang, Y. L., Lin, Y. C., Lin, C. C., Chen, W. M., Chen, B. P. C. and Lee, H.
Cell Physiol Biochem. 2018 Oct 12, [epub ahead of print]

Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming
Koutsioumpa, M., Hatziapostolou, M., Polytarchou, C., Tolosa, E. J., Almada, L. L., Mahurkar-Joshi, S., Williams, J., Tirado-Rodriguez, A. B., Huerta-Yepez, S., Karavias, D., Kourea, H., Poultsides, G. A., Struhl, K., Dawson, D. W., Donahue, T. R., Fernandez-Zapico, M. E. and Iliopoulos, D.
Gut. 2018 Oct 18, [epub ahead of print]

Targeting PDK4 inhibits breast cancer metabolism
Guda, M. R., Asuthkar, S., Labak, C. M., Tsung, A. J., Alexandrov, I., Mackenzie, M. J., Prasad, D. V. and Velpula, K. K.
Am J Cancer Res. 2018 Sep 1, 8(9):1725-1738.

Romina: A powerful strawberry with in vitro efficacy against uterine leiomyoma cells
Giampieri, F., Islam, M. S., Greco, S., Gasparrini, M., Forbes Hernandez, T. Y., Delli Carpini, G., Giannubilo, S. R., Ciavattini, A., Mezzetti, B., Mazzoni, L., Capocasa, F., Castellucci, M., Battino, M. and Ciarmela, P.
J Cell Physiol. 2019 May 1, 234(5):7622-7633.

Silencing of FOXO6 inhibits the proliferation, invasion, and glycolysis in colorectal cancer cells
Li, Q., Tang, H., Hu, F. and Qin, C.
J Cell Biochem. 2019 Mar 1, 120(3):3853-3860.

Targeting glucose and glutamine metabolism combined with radiation therapy in non-small cell lung cancer
Meijer, T. W. H., Peeters, W. J. M., Dubois, L. J., van Gisbergen, M. W., Biemans, R., Venhuizen, J. H., Span, P. N. and Bussink, J.
Lung Cancer. 2018 Dec 1, 126(32-40.

MicroRNA-23a promotes colorectal cancer cell survival by targeting PDK4
Deng, Y. H., Deng, Z. H., Hao, H., Wu, X. L., Gao, H., Tang, S. H. and Tang, H.
Exp Cell Res. 2018 Dec 15, 373(1-2):171-179.

Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma
Hoang-Minh, L. B., Siebzehnrubl, F. A., Yang, C., Suzuki-Hatano, S., Dajac, K., Loche, T., Andrews, N., Schmoll Massari, M., Patel, J., Amin, K., Vuong, A., Jimenez-Pascual, A., Kubilis, P., Garrett, T. J., Moneypenny, C., Pacak, C. A., Huang, J., Sayour, E. J., Mitchell, D. A., Sarkisian, M. R., Reynolds, B. A. and Deleyrolle, L. P.
EMBO J. 2018 Dec 3, 37(23).

The p38alpha Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1alpha
Simoes-Sousa, S., Littler, S., Thompson, S. L., Minshall, P., Whalley, H., Bakker, B., Belkot, K., Moralli, D., Bronder, D., Tighe, A., Spierings, D. C. J., Bah, N., Graham, J., Nelson, L., Green, C. M., Foijer, F., Townsend, P. A. and Taylor, S. S.
Cell Rep. 2018 Oct 16, 25(3):749-760 e6.

SPARC Inhibits Metabolic Plasticity in Ovarian Cancer
Naczki, C., John, B., Patel, C., Lafferty, A., Ghoneum, A., Afify, H., White, M., Davis, A., Jin, G., Kridel, S. and Said, N.
Cancers (Basel). 2018 Oct 16, 10(10).

Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma
Ananieva, E. A., Bostic, J. N., Torres, A. A., Glanz, H. R., McNitt, S. M., Brenner, M. K., Boyer, M. P., Addington, A. K. and Hutson, S. M.
Br J Cancer. 2018 Oct, 119(8):1009-1017.

Chronic Lymphocytic Leukemia - Methods and Protocols
Malek, S. N.
2019 Jan 1, [epub ahead of print]

Targeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC
Lee, S., Lee, J. S., Seo, J., Lee, S. H., Kang, J. H., Song, J. and Kim, S. Y.
Sci Rep. 2018 Oct 24, 8(1):15707.

Forcing ATGL expression in hepatocarcinoma cells imposes glycolytic rewiring through PPAR-alpha/p300-mediated acetylation of p53
Di Leo, L., Vegliante, R., Ciccarone, F., Salvatori, I., Scimeca, M., Bonanno, E., Sagnotta, A., Grazi, G. L., Aquilano, K. and Ciriolo, M. R.
Oncogene. 2018 Oct 26, [epub ahead of print]

IRE1alpha-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity
Song, M., Sandoval, T. A., Chae, C. S., Chopra, S., Tan, C., Rutkowski, M. R., Raundhal, M., Chaurio, R. A., Payne, K. K., Konrad, C., Bettigole, S. E., Shin, H. R., Crowley, M. J. P., Cerliani, J. P., Kossenkov, A. V., Motorykin, I., Zhang, S., Manfredi, G., Zamarin, D., Holcomb, K., Rodriguez, P. C., Rabinovich, G. A., Conejo-Garcia, J. R., Glimcher, L. H. and Cubillos-Ruiz, J. R.
Nature. 2018 Oct 1, 562(7727):423-428.

Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction
Cheng, C. T., Qi, Y., Wang, Y. C., Chi, K. K., Chung, Y., Ouyang, C., Chen, Y. R., Oh, M. E., Sheng, X., Tang, Y., Liu, Y. R., Lin, H. H., Kuo, C. Y., Schones, D., Vidal, C. M., Chu, J. C., Wang, H. J., Chen, Y. H., Miller, K. M., Chu, P., Yen, Y., Jiang, L., Kung, H. J. and Ann, D. K.
Commun Biol. 2018 Oct 26, 1:178.

18beta-glycyrrhetinic acid inhibited mitochondrial energy metabolism and gastric carcinogenesis through methylation regulated TLR2 signaling pathway
Cao, D., Wu, Y., Jia, Z., Zhao, D., Zhang, Y., Zhou, T., Wu, M., Zhang, H., Tsukamoto, T., Oshima, M., Jiang, J. and Cao, X.
Carcinogenesis. 2018 Oct 26, [epub ahead of print]

NADPH oxidase NOX4 is a glycolytic regulator through mROS-HIF1alpha axis in thyroid carcinomas
Tang, P., Dang, H., Huang, J., Xu, T., Yuan, P., Hu, J. and Sheng, J. F.
Sci Rep. 2018 Oct 26, 8(1):15897.

Collagen prolyl 4-hydroxylase 1 is essential for HIF-1alpha stabilization and TNBC chemoresistance
Xiong, G., Stewart, R. L., Chen, J., Gao, T., Scott, T. L., Samayoa, L. M., O'Connor, K., Lane, A. N. and Xu, R.
Nat Commun. 2018 Oct 26, 9(1):4456.

Tumour-originated exosomal miR-155 triggers cancer-associated cachexia to promote tumour progression
Wu, Q., Sun, S., Li, Z., Yang, Q., Li, B., Zhu, S., Wang, L., Wu, J., Yuan, J., Yang, C., Li, J. and Sun, S.
Mol Cancer. 2018 Oct 25, 17(1):155.

Reduction of Cisplatin-Induced Ototoxicity without Compromising Its Antitumor Activity
Surnar, B., Kolishetti, N., Basu, U., Ahmad, A., Goka, E., Marples, B., Kolb, D., Lippman, M. E. and Dhar, S.
Biochemistry. 2018 Nov 20, 57(46):6500-6513.

Targeting Tumor Microenvironment by Bioreduction-Activated Nanoparticles for Light-Triggered Virotherapy
Tseng, S. J., Kempson, I. M., Huang, K. Y., Li, H. J., Fa, Y. C., Ho, Y. C., Liao, Z. X. and Yang, P. C.
ACS Nano. 2018 Oct 23, 12(10):9894-9902.

Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics
Zhang, W., Hu, X., Chakravarty, H., Yang, Z. and Tam, K. Y.
ACS Comb Sci. 2018 Nov 12, 20(11):660-671.

Cardiovascular Research

Empagliflozin Ammeliorates High Glucose Induced-Cardiac Dysfuntion in Human iPSC-Derived Cardiomyocytes
Ng, K. M., Lau, Y. M., Dhandhania, V., Cai, Z. J., Lee, Y. K., Lai, W. H., Tse, H. F. and Siu, C. W.
Sci Rep. 2018 Oct 5, 8(1):14872.

Overexpression of miR-142-3p improves mitochondrial function in cardiac hypertrophy
Liu, B. L., Cheng, M., Hu, S., Wang, S., Wang, L., Tu, X., Huang, C. X., Jiang, H. and Wu, G.
Biomed Pharmacother. 2018 Dec 1, 108(1347-1356.

Cardiac Dysfunction in the Sigma 1 Receptor Knockout Mouse Associated With Impaired Mitochondrial Dynamics and Bioenergetics
Abdullah, C. S., Alam, S., Aishwarya, R., Miriyala, S., Panchatcharam, M., Bhuiyan, M. A. N., Peretik, J. M., Orr, A. W., James, J., Osinska, H., Robbins, J., Lorenz, J. N. and Bhuiyan, M. S.
J Am Heart Assoc. 2018 Oct 16, 7(20):e009775.

Diabetic Cardiomyopathy Modelling Using Induced Pluripotent Stem Cell Derived Cardiomyocytes: Recent Advances and Emerging Models
Graneli, C., Hicks, R., Brolen, G., Synnergren, J. and Sartipy, P.
Stem Cell Rev. 2019 Feb, 15(1):13-22.

Stress response protein GJA1-20k promotes mitochondrial biogenesis, metabolic quiescence, and cardioprotection against ischemia/reperfusion injury
Basheer, W. A., Fu, Y., Shimura, D., Xiao, S., Agvanian, S., Hernandez, D. M., Hitzeman, T. C., Hong, T. and Shaw, R. M.
JCI Insight. 2018 Oct 18, 3(20).

Shock Wave Therapy Enhances Mitochondrial Delivery into Target Cells and Protects against Acute Respiratory Distress Syndrome
Lin, K. C., Wallace, C. G., Yin, T. C., Sung, P. H., Chen, K. H., Lu, H. I., Chai, H. T., Chen, C. H., Chen, Y. L., Li, Y. C., Shao, P. L., Lee, M. S., Sheu, J. J. and Yip, H. K.
Mediators Inflamm. 2018 Oct 21, 2018:5425346.

A modified method for isolation of human cardiomyocytes to model cardiac diseases
Guo, G. R., Chen, L., Rao, M., Chen, K., Song, J. P. and Hu, S. S.
J Transl Med. 2018 Oct 22, 16(1):288.

Lipopolysaccharide-induced proliferation and glycolysis in airway smooth muscle cells via activation of Drp1
Zhang, L., Ma, C., Wang, X., He, S., Li, Q., Zhou, Y., Liu, Y., Zhang, M., Yu, X., Zhao, X., Li, F. and Zhu, D. L.
J Cell Physiol. 2018 Oct 14, [epub ahead of print]

Intracellular cholesterol accumulation and coenzyme Q10 deficiency in Familial Hypercholesterolemia
Suarez-Rivero, J. M., de la Mata, M., Pavon, A. D., Villanueva-Paz, M., Povea-Cabello, S., Cotan, D., Alvarez-Cordoba, M., Villalon-Garcia, I., Ybot-Gonzalez, P., Salas, J. J., Muniz, O., Cordero, M. D. and Sanchez-Alcazar, J. A.
Biochim Biophys Acta Mol Basis Dis. 2018 Dec 1, 1864(12):3697-3713.

Cell Physiology Research

Impaired myogenic development, differentiation and function in hESC-derived SMA myoblasts and myotubes
Hellbach, N., Peterson, S., Haehnke, D., Shankar, A., LaBarge, S., Pivaroff, C., Saenger, S., Thomas, C., McCarthy, K., Ebeling, M., Hayhurst Bennett, M., Schmidt, U. and Metzger, F.
PLoS One. 2018 Oct 10, 13(10):e0205589.

Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFkappaB
O'Leary, M. F., Wallace, G. R., Davis, E. T., Murphy, D. P., Nicholson, T., Bennett, A. J., Tsintzas, K. and Jones, S. W.
Sci Rep. 2018 Oct 18, 8(1):15360.

Stress response protein GJA1-20k promotes mitochondrial biogenesis, metabolic quiescence, and cardioprotection against ischemia/reperfusion injury
Basheer, W. A., Fu, Y., Shimura, D., Xiao, S., Agvanian, S., Hernandez, D. M., Hitzeman, T. C., Hong, T. and Shaw, R. M.
JCI Insight. 2018 Oct 18, 3(20).

Age-dependent changes in intervertebral disc cell mitochondria and bioenergetics
Hartman, R., Patil, P., Tisherman, R., St Croix, C., Niedernhofer, L. J., Robbins, P. D., Ambrosio, F., Van Houten, B., Sowa, G. and Vo, N.
Eur Cell Mater. 2018 Oct 18, 36(171-183.

Platelet releasate promotes skeletal myogenesis by increasing muscle stem cell commitment to differentiation and accelerates muscle regeneration following acute injury
Scully, D., Sfyri, P., Verpoorten, S., Papadopoulos, P., Munoz-Turrillas, M. C., Mitchell, R., Aburima, A., Patel, K., Gutierrez, L., Naseem, K. M. and Matsakas, A.
Acta Physiol (Oxf). 2019 Mar 1, 225(3):e13207.

Defining Physiological Normoxia for Improved Translation of Cell Physiology to Animal Models and Humans
Keeley, T. P. and Mann, G. E.
Physiol Rev. 2019 Jan 1, 99(1):161-234.

De novo NAD(+) synthesis enhances mitochondrial function and improves health
Katsyuba, E., Mottis, A., Zietak, M., De Franco, F., van der Velpen, V., Gariani, K., Ryu, D., Cialabrini, L., Matilainen, O., Liscio, P., Giacche, N., Stokar-Regenscheit, N., Legouis, D., de Seigneux, S., Ivanisevic, J., Raffaelli, N., Schoonjans, K., Pellicciari, R. and Auwerx, J.
Nature. 2018 Nov 1, 563(7731):354-359.

APP promotes osteoblast survival and bone formation by regulating mitochondrial function and preventing oxidative stress
Pan, J. X., Tang, F., Xiong, F., Xiong, L., Zeng, P., Wang, B., Zhao, K., Guo, H., Shun, C., Xia, W. F., Mei, L. and Xiong, W. C.
Cell Death Dis. 2018 Oct 22, 9(11):1077.

Lipopolysaccharide-induced proliferation and glycolysis in airway smooth muscle cells via activation of Drp1
Zhang, L., Ma, C., Wang, X., He, S., Li, Q., Zhou, Y., Liu, Y., Zhang, M., Yu, X., Zhao, X., Li, F. and Zhu, D. L.
J Cell Physiol. 2018 Oct 14, [epub ahead of print]

Mitochondrial oxidation of the carbohydrate fuel is required for neural precursor/stem cell function and postnatal cerebellar development
Zheng, H., Yu, W. M., Shen, J., Kang, S., Hambardzumyan, D., Li, J. Y., Shen, Y., Kenney, A. M., Chen, J. and Qu, C. K.
Sci Adv. 2018 Oct 10, 4(10):eaat2681.

Cellular metabolic rates and oxidative stress profiles in primary fibroblast cells isolated from virgin females, reproductively experienced females, and male Sprague-Dawley rats
Winward, J. D., Ragan, C. M. and Jimenez, A. G.
Physiol Rep. 2018 Oct 1, 6(20):e13909.

Drug Discovery

Drug Synergy Slows Aging and Improves Healthspan through IGF and SREBP Lipid Signaling
Admasu, T. D., Chaithanya Batchu, K., Barardo, D., Ng, L. F., Lam, V. Y. M., Xiao, L., Cazenave-Gassiot, A., Wenk, M. R., Tolwinski, N. S. and Gruber, J.
Dev Cell. 2018 Oct 8, 47(1):67-79 e5.

Effect of Differences in Metabolic Activity of Melanoma Models on Response to Lonidamine plus Doxorubicin
Nath, K., Roman, J., Nelson, D. S., Guo, L., Lee, S. C., Orlovskiy, S., Muriuki, K., Heitjan, D. F., Pickup, S., Leeper, D. B., Blair, I. A., Putt, M. E. and Glickson, J. D.
Sci Rep. 2018 Oct 2, 8(1):14654.

Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment
Ma, J., Huo, X., Jarpe, M. B., Kavelaars, A. and Heijnen, C. J.
Acta Neuropathol Commun. 2018 Oct 1, 6(1):103.

LDeprenyl exerts cytotoxicity towards acute myeloid leukemia through inhibition of mitochondrial respiration
Ryu, I., Ryu, M. J., Han, J., Kim, S. J., Lee, M. J., Ju, X., Yoo, B. H., Lee, Y. L., Jang, Y., Song, I. C., Chung, W., Oh, E., Heo, J. Y. and Kweon, G. R.
Oncol Rep. 2018 Dec 1, 40(6):3869-3878.

Empagliflozin Ammeliorates High Glucose Induced-Cardiac Dysfuntion in Human iPSC-Derived Cardiomyocytes
Ng, K. M., Lau, Y. M., Dhandhania, V., Cai, Z. J., Lee, Y. K., Lai, W. H., Tse, H. F. and Siu, C. W.
Sci Rep. 2018 Oct 5, 8(1):14872.

Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury
Longo, D. M., Woodhead, J. L., Walker, P., Heredi-Szabo, K., Mogyorosi, K., Wolenski, F. S., Dragan, Y. P., Mosedale, M., Siler, S. Q., Watkins, P. B. and Howell, B. A.
Toxicol Sci. 2019 Feb 1, 167(2):458-467.

The arginase inhibitor Nomega-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target
Ng, K. P., Manjeri, A., Lee, L. M., Chan, Z. E., Tan, C. Y., Tan, Q. D., Majeed, A., Lee, K. L., Chuah, C., Suda, T. and Ong, S. T.
PLoS One. 2018 Oct 11, 13(10):e0205254.

beta2-Adrenergic receptor modulates mitochondrial metabolism and disease progression in recurrent/metastatic HPV(+) HNSCC
Lucido, C. T., Callejas-Valera, J. L., Colbert, P. L., Vermeer, D. W., Miskimins, W. K., Spanos, W. C. and Vermeer, P. D.
Oncogenesis. 2018 Oct 8, 7(10):81.

Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis
Foo, C. S., Lupien, A., Kienle, M., Vocat, A., Benjak, A., Sommer, R., Lamprecht, D. A., Steyn, A. J. C., Pethe, K., Piton, J., Altmann, K. H. and Cole, S. T.
MBio. 2018 Oct 9, 9(5).

MicroRNA-23a promotes colorectal cancer cell survival by targeting PDK4
Deng, Y. H., Deng, Z. H., Hao, H., Wu, X. L., Gao, H., Tang, S. H. and Tang, H.
Exp Cell Res. 2018 Dec 15, 373(1-2):171-179.

Resveratrol Preconditioning Induces Genomic and Metabolic Adaptations within the Long-Term Window of Cerebral Ischemic Tolerance Leading to Bioenergetic Efficiency
Khoury, N., Xu, J., Stegelmann, S. D., Jackson, C. W., Koronowski, K. B., Dave, K. R., Young, J. I. and Perez-Pinzon, M. A.
Mol Neurobiol. 2018 Oct 20,  [epub ahead of print]

18beta-glycyrrhetinic acid inhibited mitochondrial energy metabolism and gastric carcinogenesis through methylation regulated TLR2 signaling pathway
Cao, D., Wu, Y., Jia, Z., Zhao, D., Zhang, Y., Zhou, T., Wu, M., Zhang, H., Tsukamoto, T., Oshima, M., Jiang, J. and Cao, X.
Carcinogenesis. 2018 Oct 26, [epub ahead of print]

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates
Belarif, L., Mary, C., Jacquemont, L., Mai, H. L., Danger, R., Hervouet, J., Minault, D., Thepenier, V., Nerriere-Daguin, V., Nguyen, E., Pengam, S., Largy, E., Delobel, A., Martinet, B., Le Bas-Bernardet, S., Brouard, S., Soulillou, J. P., Degauque, N., Blancho, G., Vanhove, B. and Poirier, N.
Nat Commun. 2018 Oct 26, 9(1):4483.

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis
Soberanes, S., Misharin, A. V., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., Chen, C. I., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Antalek, M., Abdala-Valencia, H., Chiarella, S. E., Sun, K. A., Woods, P. S., Ghio, A. J., Jain, M., Perlman, H., Ridge, K. M., Morimoto, R. I., Sznajder, J. I., Balch, W. E., Bhorade, S. M., Bharat, A., Prakriya, M., Chandel, N. S., Mutlu, G. M. and Budinger, G. R. S.
Cell Metab. 2019 Feb 5, 29(2):335-347 e5.

Reduction of Cisplatin-Induced Ototoxicity without Compromising Its Antitumor Activity
Surnar, B., Kolishetti, N., Basu, U., Ahmad, A., Goka, E., Marples, B., Kolb, D., Lippman, M. E. and Dhar, S.
Biochemistry. 2018 Nov 20, 57(46):6500-6513.

Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics
Zhang, W., Hu, X., Chakravarty, H., Yang, Z. and Tam, K. Y.
ACS Comb Sci. 2018 Nov 12, 20(11):660-671.

Targeting Tumor Microenvironment by Bioreduction-Activated Nanoparticles for Light-Triggered Virotherapy
Tseng, S. J., Kempson, I. M., Huang, K. Y., Li, H. J., Fa, Y. C., Ho, Y. C., Liao, Z. X. and Yang, P. C.
ACS Nano. 2018 Oct 23, 12(10):9894-9902.

Lupin seed hydrolysate promotes G-protein-coupled receptor, intracellular Ca(2+) and enhanced glycolytic metabolism-mediated insulin secretion from BRIN-BD11 pancreatic beta cells
Tapadia, M., Carlessi, R., Johnson, S., Utikar, R. and Newsholme, P.
Mol Cell Endocrinol. 2019 Jan 15, 480(83-96.

Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition
Tomilov, A., Allen, S., Hui, C. K., Bettaieb, A. and Cortopassi, G.
Pharmacol Res. 2018 Nov 1, 137(89-103.

Food & Nutritional Research

Copper deficiency-induced anemia is caused by a mitochondrial metabolic reprograming in erythropoietic cells
Jensen, E. L., Gonzalez-Ibanez, A. M., Mendoza, P., Ruiz, L. M., Riedel, C. A., Simon, F., Schuringa, J. J. and Elorza, A. A.
Metallomics. 2018 Oct 25, [epub ahead of print]

Romina: A powerful strawberry with in vitro efficacy against uterine leiomyoma cells
Giampieri, F., Islam, M. S., Greco, S., Gasparrini, M., Forbes Hernandez, T. Y., Delli Carpini, G., Giannubilo, S. R., Ciavattini, A., Mezzetti, B., Mazzoni, L., Capocasa, F., Castellucci, M., Battino, M. and Ciarmela, P.
J Cell Physiol. 2019 May 1, 234(5):7622-7633.

Hepatobiology Research

Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury
Longo, D. M., Woodhead, J. L., Walker, P., Heredi-Szabo, K., Mogyorosi, K., Wolenski, F. S., Dragan, Y. P., Mosedale, M., Siler, S. Q., Watkins, P. B. and Howell, B. A.
Toxicol Sci. 2019 Feb 1, 167(2):458-467.

Systemic messenger RNA as an etiological treatment for acute intermittent porphyria
Jiang, L., Berraondo, P., Jerico, D., Guey, L. T., Sampedro, A., Frassetto, A., Benenato, K. E., Burke, K., Santamaria, E., Alegre, M., Pejenaute, A., Kalariya, M., Butcher, W., Park, J. S., Zhu, X., Sabnis, S., Kumarasinghe, E. S., Salerno, T., Kenney, M., Lukacs, C. M., Avila, M. A., Martini, P. G. V. and Fontanellas, A.
Nat Med. 2018 Dec  24(12):1899-1909.

Imatinib reduces non-alcoholic fatty liver disease in obese mice by targeting inflammatory and lipogenic pathways in macrophages and liver
AlAsfoor, S., Rohm, T. V., Bosch, A. J. T., Dervos, T., Calabrese, D., Matter, M. S., Weber, A. and Cavelti-Weder, C.
Sci Rep. 2018 Oct 17, 8(1):15331.

Metabolic Remodeling during Liver Regeneration
Caldez, M. J., Van Hul, N., Koh, H. W. L., Teo, X. Q., Fan, J. J., Tan, P. Y., Dewhurst, M. R., Too, P. G., Talib, S. Z. A., Chiang, B. E., Stunkel, W., Yu, H., Lee, P., Fuhrer, T., Choi, H., Bjorklund, M. and Kaldis, P.
Dev Cell. 2018 Nov 19, 47(4):425-438 e5.

LXRalpha Promotes Hepatosteatosis in Part Through Activation of MicroRNA-378 Transcription and Inhibition of Ppargc1beta Expression
Zhang, T., Duan, J., Zhang, L., Li, Z., Steer, C. J., Yan, G. and Song, G.
Hepatology. 2018 Oct 3, [epub ahead of print]

Immunology Research

Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis
Barth, N. D., Marwick, J. A., Heeb, M. J., Gale, A. J., Rossi, A. G. and Dransfield, I.
J Immunol. 2018 Nov 1, 201(9):2602-2611.

HIV-1 Nef Disrupts CD4(+) T Lymphocyte Polarity, Extravasation, and Homing to Lymph Nodes via Its Nef-Associated Kinase Complex Interface
Lamas-Murua, M., Stolp, B., Kaw, S., Thoma, J., Tsopoulidis, N., Trautz, B., Ambiel, I., Reif, T., Arora, S., Imle, A., Tibroni, N., Wu, J., Cui, G., Stein, J. V., Tanaka, M., Lyck, R. and Fackler, O. T.
J Immunol. 2018 Nov 1, 201(9):2731-2743.

Commitment to Aerobic Glycolysis Sustains Immunosuppression of Human Mesenchymal Stem Cells
Liu, Y., Yuan, X., Munoz, N., Logan, T. M. and Ma, T.
Stem Cells Transl Med. 2019 Jan 1, 8(1):93-106.

Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation
Lee, S. Y. and Long, F.
J Clin Invest. 2018 Dec 3, 128(12):5573-5586.

Impaired myogenic development, differentiation and function in hESC-derived SMA myoblasts and myotubes
Hellbach, N., Peterson, S., Haehnke, D., Shankar, A., LaBarge, S., Pivaroff, C., Saenger, S., Thomas, C., McCarthy, K., Ebeling, M., Hayhurst Bennett, M., Schmidt, U. and Metzger, F.
PLoS One. 2018 Oct 10, 13(10):e0205589.

miR-31 regulates energy metabolism and is suppressed in T cells from patients with Sjogren's syndrome
Johansson, A., Nyberg, W. A., Sjostrand, M., Moruzzi, N., Bergman, P., Khademi, M., Andersson, M., Piehl, F., Berggren, P. O., Covacu, R., Jagodic, M. and Espinosa, A.
Eur J Immunol. 2019 Feb 1, 49(2):313-322.

Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents beta Cell Death via ATG16L1 Interaction and Autophagy Regulation
King, B. C., Kulak, K., Krus, U., Rosberg, R., Golec, E., Wozniak, K., Gomez, M. F., Zhang, E., O'Connell, D. J., Renstrom, E. and Blom, A. M.
Cell Metab. 2019 Jan 8, 29(1):202-210 e6.

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity
Dominguez-Andres, J., Novakovic, B., Li, Y., Scicluna, B. P., Gresnigt, M. S., Arts, R. J. W., Oosting, M., Moorlag, S., Groh, L. A., Zwaag, J., Koch, R. M., Ter Horst, R., Joosten, L. A. B., Wijmenga, C., Michelucci, A., van der Poll, T., Kox, M., Pickkers, P., Kumar, V., Stunnenberg, H. and Netea, M. G.
Cell Metab. 2019 Jan 8, 29(1):211-220 e5.

Regnase-1 controls colon epithelial regeneration via regulation of mTOR and purine metabolism
Nagahama, Y., Shimoda, M., Mao, G., Singh, S. K., Kozakai, Y., Sun, X., Motooka, D., Nakamura, S., Tanaka, H., Satoh, T., Maeda, K. and Akira, S.
Proc Natl Acad Sci U S A. 2018 Oct 23, 115(43):11036-11041.

Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFkappaB
O'Leary, M. F., Wallace, G. R., Davis, E. T., Murphy, D. P., Nicholson, T., Bennett, A. J., Tsintzas, K. and Jones, S. W.
Sci Rep. 2018 Oct 18, 8(1):15360.

Imatinib reduces non-alcoholic fatty liver disease in obese mice by targeting inflammatory and lipogenic pathways in macrophages and liver
AlAsfoor, S., Rohm, T. V., Bosch, A. J. T., Dervos, T., Calabrese, D., Matter, M. S., Weber, A. and Cavelti-Weder, C.
Sci Rep. 2018 Oct 17, 8(1):15331.

Platelet releasate promotes skeletal myogenesis by increasing muscle stem cell commitment to differentiation and accelerates muscle regeneration following acute injury
Scully, D., Sfyri, P., Verpoorten, S., Papadopoulos, P., Munoz-Turrillas, M. C., Mitchell, R., Aburima, A., Patel, K., Gutierrez, L., Naseem, K. M. and Matsakas, A.
Acta Physiol (Oxf). 2019 Mar 1, 225(3):e13207.

IRE1alpha-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity
Song, M., Sandoval, T. A., Chae, C. S., Chopra, S., Tan, C., Rutkowski, M. R., Raundhal, M., Chaurio, R. A., Payne, K. K., Konrad, C., Bettigole, S. E., Shin, H. R., Crowley, M. J. P., Cerliani, J. P., Kossenkov, A. V., Motorykin, I., Zhang, S., Manfredi, G., Zamarin, D., Holcomb, K., Rodriguez, P. C., Rabinovich, G. A., Conejo-Garcia, J. R., Glimcher, L. H. and Cubillos-Ruiz, J. R.
Nature. 2018 Oct 1, 562(7727):423-428.

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates
Belarif, L., Mary, C., Jacquemont, L., Mai, H. L., Danger, R., Hervouet, J., Minault, D., Thepenier, V., Nerriere-Daguin, V., Nguyen, E., Pengam, S., Largy, E., Delobel, A., Martinet, B., Le Bas-Bernardet, S., Brouard, S., Soulillou, J. P., Degauque, N., Blancho, G., Vanhove, B. and Poirier, N.
Nat Commun. 2018 Oct 26, 9(1):4483.

Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis
Scott, N. A., Andrusaite, A., Andersen, P., Lawson, M., Alcon-Giner, C., Leclaire, C., Caim, S., Le Gall, G., Shaw, T., Connolly, J. P. R., Roe, A. J., Wessel, H., Bravo-Blas, A., Thomson, C. A., Kastele, V., Wang, P., Peterson, D. A., Bancroft, A., Li, X., Grencis, R., Mowat, A. M., Hall, L. J., Travis, M. A., Milling, S. W. F. and Mann, E. R.
Sci Transl Med. 2018 Oct 24, 10(464).

Evidence for a direct link between PAD4-mediated citrullination and the oxidative burst in human neutrophils
Zhou, Y., An, L. L., Chaerkady, R., Mittereder, N., Clarke, L., Cohen, T. S., Chen, B., Hess, S., Sims, G. P. and Mustelin, T.
Sci Rep. 2018 Oct 15, 8(1):15228.

beta-hydroxy-beta-methylbutyrate (HMB) improves mitochondrial function in myocytes through pathways involving PPARbeta/delta and CDK4
Zhong, Y., Zeng, L., Deng, J., Duan, Y. and Li, F.
Nutrition. 2019 Apr 1, 60(217-226.

Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells
Stone, O. A., El-Brolosy, M., Wilhelm, K., Liu, X., Romao, A. M., Grillo, E., Lai, J. K. H., Gunther, S., Jeratsch, S., Kuenne, C., Lee, I. C., Braun, T., Santoro, M. M., Locasale, J. W., Potente, M. and Stainier, D. Y. R.
Nat Commun. 2018 Oct 9, 9(1):4077.

Peroxisome Proliferator-Activated Receptor-delta Supports the Metabolic Requirements of Cell Growth in TCRbeta-Selected Thymocytes and Peripheral CD4(+) T Cells
Zhao, F. L., Ahn, J. J., Chen, E. L. Y., Yi, T. J., Stickle, N. H., Spaner, D., Zuniga-Pflucker, J. C. and Dunn, S. E.
J Immunol. 2018 Nov 1, 201(9):2664-2682.

Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity
Yao, Y., Jeyanathan, M., Haddadi, S., Barra, N. G., Vaseghi-Shanjani, M., Damjanovic, D., Lai, R., Afkhami, S., Chen, Y., Dvorkin-Gheva, A., Robbins, C. S., Schertzer, J. D. and Xing, Z.
Cell. 2018 Nov 29, 175(6):1634-1650 e17.

Infectious Disease Research

HIV-1 Nef Disrupts CD4(+) T Lymphocyte Polarity, Extravasation, and Homing to Lymph Nodes via Its Nef-Associated Kinase Complex Interface
Lamas-Murua, M., Stolp, B., Kaw, S., Thoma, J., Tsopoulidis, N., Trautz, B., Ambiel, I., Reif, T., Arora, S., Imle, A., Tibroni, N., Wu, J., Cui, G., Stein, J. V., Tanaka, M., Lyck, R. and Fackler, O. T.
J Immunol. 2018 Nov 1, 201(9):2731-2743.

Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis
Foo, C. S., Lupien, A., Kienle, M., Vocat, A., Benjak, A., Sommer, R., Lamprecht, D. A., Steyn, A. J. C., Pethe, K., Piton, J., Altmann, K. H. and Cole, S. T.
MBio. 2018 Oct 9, 9(5).

Chlamydia trachomatis targets mitochondrial dynamics to promote intracellular survival and proliferation
Kurihara, Y., Itoh, R., Shimizu, A., Walenna, N. F., Chou, B., Ishii, K., Soejima, T., Fujikane, A. and Hiromatsu, K.
Cell Microbiol. 2019 Jan 1, 21(1):e12962.

Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis
Scott, N. A., Andrusaite, A., Andersen, P., Lawson, M., Alcon-Giner, C., Leclaire, C., Caim, S., Le Gall, G., Shaw, T., Connolly, J. P. R., Roe, A. J., Wessel, H., Bravo-Blas, A., Thomson, C. A., Kastele, V., Wang, P., Peterson, D. A., Bancroft, A., Li, X., Grencis, R., Mowat, A. M., Hall, L. J., Travis, M. A., Milling, S. W. F. and Mann, E. R.
Sci Transl Med. 2018 Oct 24, 10(464).

Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity
Yao, Y., Jeyanathan, M., Haddadi, S., Barra, N. G., Vaseghi-Shanjani, M., Damjanovic, D., Lai, R., Afkhami, S., Chen, Y., Dvorkin-Gheva, A., Robbins, C. S., Schertzer, J. D. and Xing, Z.
Cell. 2018 Nov 29, 175(6):1634-1650 e17.

Microbial Research

Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis
Foo, C. S., Lupien, A., Kienle, M., Vocat, A., Benjak, A., Sommer, R., Lamprecht, D. A., Steyn, A. J. C., Pethe, K., Piton, J., Altmann, K. H. and Cole, S. T.
MBio. 2018 Oct 9, 9(5).

Chlamydia trachomatis targets mitochondrial dynamics to promote intracellular survival and proliferation
Kurihara, Y., Itoh, R., Shimizu, A., Walenna, N. F., Chou, B., Ishii, K., Soejima, T., Fujikane, A. and Hiromatsu, K.
Cell Microbiol. 2019 Jan 1, 21(1):e12962.

Mitochondrial Disease Reseach

Preliminary observations of mitochondrial dysfunction in Prader-Willi syndrome
Butler, M. G., Hossain, W. A., Tessman, R. and Krishnamurthy, P. C.
Am J Med Genet A. 2018 Dec 1, 176(12):2587-2594.

A deafness-associated mitochondrial DNA mutation altered the tRNA(Ser(UCN)) metabolism and mitochondrial function
Xue, L., Chen, Y., Tang, X., Yao, J., Huang, H., Wang, M., Ye, S., Wang, M. and Guan, M. X.
Mitochondrion. 2018 Oct 15, [epub ahead of print]

Model Organisms

Drug Synergy Slows Aging and Improves Healthspan through IGF and SREBP Lipid Signaling
Admasu, T. D., Chaithanya Batchu, K., Barardo, D., Ng, L. F., Lam, V. Y. M., Xiao, L., Cazenave-Gassiot, A., Wenk, M. R., Tolwinski, N. S. and Gruber, J.
Dev Cell. 2018 Oct 8, 47(1):67-79 e5.

Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer
Eichenlaub, T., Villadsen, R., Freitas, F. C. P., Andrejeva, D., Aldana, B. I., Nguyen, H. T., Petersen, O. W., Gorodkin, J., Herranz, H. and Cohen, S. M.
Curr Biol. 2018 Oct 22, 28(20):3220-3228 e6.

Biological impacts of organophosphates chlorpyrifos and diazinon on development, mitochondrial bioenergetics, and locomotor activity in zebrafish (Danio rerio)
Cao, F., Souders, C. L., 2nd, Li, P., Pang, S., Qiu, L. and Martyniuk, C. J.
Neurotoxicol Teratol. 2018 Oct 2, [epub ahead of print]

De novo NAD(+) synthesis enhances mitochondrial function and improves health
Katsyuba, E., Mottis, A., Zietak, M., De Franco, F., van der Velpen, V., Gariani, K., Ryu, D., Cialabrini, L., Matilainen, O., Liscio, P., Giacche, N., Stokar-Regenscheit, N., Legouis, D., de Seigneux, S., Ivanisevic, J., Raffaelli, N., Schoonjans, K., Pellicciari, R. and Auwerx, J.
Nature. 2018 Nov 1, 563(7731):354-359.

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates
Belarif, L., Mary, C., Jacquemont, L., Mai, H. L., Danger, R., Hervouet, J., Minault, D., Thepenier, V., Nerriere-Daguin, V., Nguyen, E., Pengam, S., Largy, E., Delobel, A., Martinet, B., Le Bas-Bernardet, S., Brouard, S., Soulillou, J. P., Degauque, N., Blancho, G., Vanhove, B. and Poirier, N.
Nat Commun. 2018 Oct 26, 9(1):4483.

Neurobiology Research

Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment
Ma, J., Huo, X., Jarpe, M. B., Kavelaars, A. and Heijnen, C. J.
Acta Neuropathol Commun. 2018 Oct 1, 6(1):103.

Bioenergetics in fibroblasts of patients with Huntington disease are associated with age at onset
Gardiner, S. L., Milanese, C., Boogaard, M. W., Buijsen, R. A. M., Hogenboom, M., Roos, R. A. C., Mastroberardino, P. G., van Roon-Mom, W. M. C. and Aziz, N. A.
Neurol Genet. 2018 Oct, 4(5):e275.

Systemic messenger RNA as an etiological treatment for acute intermittent porphyria
Jiang, L., Berraondo, P., Jerico, D., Guey, L. T., Sampedro, A., Frassetto, A., Benenato, K. E., Burke, K., Santamaria, E., Alegre, M., Pejenaute, A., Kalariya, M., Butcher, W., Park, J. S., Zhu, X., Sabnis, S., Kumarasinghe, E. S., Salerno, T., Kenney, M., Lukacs, C. M., Avila, M. A., Martini, P. G. V. and Fontanellas, A.
Nat Med. 2018 Dec  24(12):1899-1909.

Assessing the Effects of Ripasudil, a Novel Rho Kinase Inhibitor, on Human Corneal Endothelial Cell Health
Goldstein, A. S., Aldrich, B. T., Skeie, J. M., Schmidt, G. A., Reed, C. R., Zimmerman, M. B. and Greiner, M. A.
J Ocul Pharmacol Ther. 2018 Oct 12, [epub ahead of print]

Bi-allelic mutations of LONP1 encoding the mitochondrial LonP1 protease cause pyruvate dehydrogenase deficiency and profound neurodegeneration with progressive cerebellar atrophy
Nimmo, G. A. M., Venkatesh, S., Pandey, A. K., Marshall, C. R., Hazrati, L. N., Blaser, S., Ahmed, S., Cameron, J., Singh, K., Ray, P. N., Suzuki, C. K. and Yoon, G.
Hum Mol Genet. 2019 Jan 15, 28(2):290-306.

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells
Smith, A. M., Depp, C., Ryan, B. J., Johnston, G. I., Alegre-Abarrategui, J., Evetts, S., Rolinski, M., Baig, F., Ruffmann, C., Simon, A. K., Hu, M. T. M. and Wade-Martins, R.
Mov Disord. 2018 Oct 1, 33(10):1580-1590.

Resveratrol Preconditioning Induces Genomic and Metabolic Adaptations within the Long-Term Window of Cerebral Ischemic Tolerance Leading to Bioenergetic Efficiency
Khoury, N., Xu, J., Stegelmann, S. D., Jackson, C. W., Koronowski, K. B., Dave, K. R., Young, J. I. and Perez-Pinzon, M. A.
Mol Neurobiol. 2018 Oct 20,  [epub ahead of print]

HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons
Kishinevsky, S., Wang, T., Rodina, A., Chung, S. Y., Xu, C., Philip, J., Taldone, T., Joshi, S., Alpaugh, M. L., Bolaender, A., Gutbier, S., Sandhu, D., Fattahi, F., Zimmer, B., Shah, S. K., Chang, E., Inda, C., Koren, J., 3rd, Saurat, N. G., Leist, M., Gross, S. S., Seshan, V. E., Klein, C., Tomishima, M. J., Erdjument-Bromage, H., Neubert, T. A., Henrickson, R. C., Chiosis, G. and Studer, L.
Nat Commun. 2018 Oct 19, 9(1):4345.

c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD(+) cleavage activity to inhibit mitochondrial respiration
Murata, H., Khine, C. C., Nishikawa, A., Yamamoto, K. I., Kinoshita, R. and Sakaguchi, M.
J Biol Chem. 2018 Dec 7, 293(49):18933-18943.

MiR-34a and stroke: Assessment of non-modifiable biological risk factors in cerebral ischemia
Ren, X., Engler-Chiurazzi, E. B., Russell, A. E., Sarkar, S. N., Rellick, S. L., Lewis, S., Corbin, D., Clapper, J. and Simpkins, J. W.
Neurochem Int. 2018 Oct 23, [epub ahead of print]

APP promotes osteoblast survival and bone formation by regulating mitochondrial function and preventing oxidative stress
Pan, J. X., Tang, F., Xiong, F., Xiong, L., Zeng, P., Wang, B., Zhao, K., Guo, H., Shun, C., Xia, W. F., Mei, L. and Xiong, W. C.
Cell Death Dis. 2018 Oct 22, 9(11):1077.

Platelets Bioenergetics Screening Reflects the Impact of Brain Abeta Plaque Accumulation in a Rat Model of Alzheimer
Prestia, F. A., Galeano, P., Martino Adami, P. V., Do Carmo, S., Castano, E. M., Cuello, A. C. and Morelli, L.
Neurochem Res. 2018 Oct 24, [epub ahead of print]

Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes
Jones, J. R., Kong, L., Hanna, M. G. t., Hoffman, B., Krencik, R., Bradley, R., Hagemann, T., Choi, J., Doers, M., Dubovis, M., Sherafat, M. A., Bhattacharyya, A., Kendziorski, C., Audhya, A., Messing, A. and Zhang, S. C.
Cell Rep. 2018 Oct 23, 25(4):947-958 e4.

Mitochondrial oxidation of the carbohydrate fuel is required for neural precursor/stem cell function and postnatal cerebellar development
Zheng, H., Yu, W. M., Shen, J., Kang, S., Hambardzumyan, D., Li, J. Y., Shen, Y., Kenney, A. M., Chen, J. and Qu, C. K.
Sci Adv. 2018 Oct 10, 4(10):eaat2681.

Basal fatty acid oxidation increases after recurrent low glucose in human primary astrocytes
Weightman Potter, P. G., Vlachaki Walker, J. M., Robb, J. L., Chilton, J. K., Williamson, R., Randall, A. D., Ellacott, K. L. J. and Beall, C.
Diabetologia. 2019 Jan 1, 62(1):187-198.

The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development
Tebbenkamp, A. T. N., Varela, L., Choi, J., Paredes, M. I., Giani, A. M., Song, J. E., Sestan-Pesa, M., Franjic, D., Sousa, A. M. M., Liu, Z. W., Li, M., Bichsel, C., Koch, M., Szigeti-Buck, K., Liu, F., Li, Z., Kawasawa, Y. I., Paspalas, C. D., Mineur, Y. S., Prontera, P., Merla, G., Picciotto, M. R., Arnsten, A. F. T., Horvath, T. L. and Sestan, N.
Cell. 2018 Nov 1, 175(4):1088-1104 e23.

Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity
Timper, K., Paeger, L., Sanchez-Lasheras, C., Varela, L., Jais, A., Nolte, H., Vogt, M. C., Hausen, A. C., Heilinger, C., Evers, N., Pospisilik, J. A., Penninger, J. M., Taylor, E. B., Horvath, T. L., Kloppenburg, P. and Bruning, J. C.
Cell Rep. 2018 Oct 9, 25(2):383-397 e10.

Obesity, Diabetes & Metabolic Diseases

Preliminary observations of mitochondrial dysfunction in Prader-Willi syndrome
Butler, M. G., Hossain, W. A., Tessman, R. and Krishnamurthy, P. C.
Am J Med Genet A. 2018 Dec 1, 176(12):2587-2594.

HB-EGF and ADAM 12S directed cellular reprogramming results in metabolically active brown adipose tissue-like cells
R. Taylor, S., A. Gemma, C., M. Cartwright, K., C. Pfeil, D., R. Miller, E., E. Long, C. and A. Harding, P.
AIMS Cell and Tissue Engineering. 2018 Sep 27, 2(4):203-219.

The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue Komakula, S. S. B., Tumova, J., Kumaraswamy, D., Burchat, N., Vartanian, V., Ye, H., Dobrzyn, A., Lloyd, R. S. and Sampath, H. Sci Rep. 2018 Oct 5, 8(1):14886.

Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents beta Cell Death via ATG16L1 Interaction and Autophagy Regulation
King, B. C., Kulak, K., Krus, U., Rosberg, R., Golec, E., Wozniak, K., Gomez, M. F., Zhang, E., O'Connell, D. J., Renstrom, E. and Blom, A. M.
Cell Metab. 2019 Jan 8, 29(1):202-210 e6.

Impact of in vitro heavy metal exposure on pancreatic beta-cell function
Dover, E. N., Patel, N. Y. and Styblo, M.
Toxicol Lett. 2018 Dec 15, 299(137-144.

Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFkappaB
O'Leary, M. F., Wallace, G. R., Davis, E. T., Murphy, D. P., Nicholson, T., Bennett, A. J., Tsintzas, K. and Jones, S. W.
Sci Rep. 2018 Oct 18, 8(1):15360.

Diabetic Cardiomyopathy Modelling Using Induced Pluripotent Stem Cell Derived Cardiomyocytes: Recent Advances and Emerging Models
Graneli, C., Hicks, R., Brolen, G., Synnergren, J. and Sartipy, P.
Stem Cell Rev. 2019 Feb, 15(1):13-22.

Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes
Clemmensen, C., Jall, S., Kleinert, M., Quarta, C., Gruber, T., Reber, J., Sachs, S., Fischer, K., Feuchtinger, A., Karlas, A., Simonds, S. E., Grandl, G., Loher, D., Sanchez-Quant, E., Keipert, S., Jastroch, M., Hofmann, S. M., Nascimento, E. B. M., Schrauwen, P., Ntziachristos, V., Cowley, M. A., Finan, B., Muller, T. D. and Tschop, M. H.
Nat Commun. 2018 Oct 23, 9(1):4304.

Lupin seed hydrolysate promotes G-protein-coupled receptor, intracellular Ca(2+) and enhanced glycolytic metabolism-mediated insulin secretion from BRIN-BD11 pancreatic beta cells
Tapadia, M., Carlessi, R., Johnson, S., Utikar, R. and Newsholme, P.
Mol Cell Endocrinol. 2019 Jan 15, 480(83-96.

Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition
Tomilov, A., Allen, S., Hui, C. K., Bettaieb, A. and Cortopassi, G.
Pharmacol Res. 2018 Nov 1, 137(89-103.

Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity
Timper, K., Paeger, L., Sanchez-Lasheras, C., Varela, L., Jais, A., Nolte, H., Vogt, M. C., Hausen, A. C., Heilinger, C., Evers, N., Pospisilik, J. A., Penninger, J. M., Taylor, E. B., Horvath, T. L., Kloppenburg, P. and Bruning, J. C.
Cell Rep. 2018 Oct 9, 25(2):383-397 e10.

Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in beta Cells
Zhang, E., Mohammed Al-Amily, I., Mohammed, S., Luan, C., Asplund, O., Ahmed, M., Ye, Y., Ben-Hail, D., Soni, A., Vishnu, N., Bompada, P., De Marinis, Y., Groop, L., Shoshan-Barmatz, V., Renstrom, E., Wollheim, C. B. and Salehi, A.
Cell Metab. 2019 Jan 8, 29(1):64-77 e6.

Asthma alleviates obesity in males through regulating metabolism and energy expenditure
Song, X., Li, B., Wang, H., Zou, X., Gao, R., Zhang, W., Shu, T., Zhao, H., Liu, B. and Wang, J.
Biochim Biophys Acta Mol Basis Dis. 2019 Feb 1, 1865(2):350-359.

Review Paper

How Supraphysiological Oxygen Levels in Standard Cell Culture Affect Oxygen-Consuming Reactions
Stuart, J. A., Fonseca, J., Moradi, F., Cunningham, C., Seliman, B., Worsfold, C. R., Dolan, S., Abando, J. and Maddalena, L. A.
Oxid Med Cell Longev. 2018 Sep 30, 2018:8238459.

Stem Cell Biology

Empagliflozin Ammeliorates High Glucose Induced-Cardiac Dysfuntion in Human iPSC-Derived Cardiomyocytes
Ng, K. M., Lau, Y. M., Dhandhania, V., Cai, Z. J., Lee, Y. K., Lai, W. H., Tse, H. F. and Siu, C. W.
Sci Rep. 2018 Oct 5, 8(1):14872.

Overexpression of miR-142-3p improves mitochondrial function in cardiac hypertrophy
Liu, B. L., Cheng, M., Hu, S., Wang, S., Wang, L., Tu, X., Huang, C. X., Jiang, H. and Wu, G.
Biomed Pharmacother. 2018 Dec 1, 108(1347-1356.

Commitment to Aerobic Glycolysis Sustains Immunosuppression of Human Mesenchymal Stem Cells
Liu, Y., Yuan, X., Munoz, N., Logan, T. M. and Ma, T.
Stem Cells Transl Med. 2019 Jan 1, 8(1):93-106.

Notch signaling suppresses glucose metabolism in mesenchymal progenitors to restrict osteoblast differentiation
Lee, S. Y. and Long, F.
J Clin Invest. 2018 Dec 3, 128(12):5573-5586.

Biological impacts of organophosphates chlorpyrifos and diazinon on development, mitochondrial bioenergetics, and locomotor activity in zebrafish (Danio rerio)
Cao, F., Souders, C. L., 2nd, Li, P., Pang, S., Qiu, L. and Martyniuk, C. J.
Neurotoxicol Teratol. 2018 Oct 2, [epub ahead of print]

Impaired myogenic development, differentiation and function in hESC-derived SMA myoblasts and myotubes
Hellbach, N., Peterson, S., Haehnke, D., Shankar, A., LaBarge, S., Pivaroff, C., Saenger, S., Thomas, C., McCarthy, K., Ebeling, M., Hayhurst Bennett, M., Schmidt, U. and Metzger, F.
PLoS One. 2018 Oct 10, 13(10):e0205589.

Copper deficiency-induced anemia is caused by a mitochondrial metabolic reprograming in erythropoietic cells
Jensen, E. L., Gonzalez-Ibanez, A. M., Mendoza, P., Ruiz, L. M., Riedel, C. A., Simon, F., Schuringa, J. J. and Elorza, A. A.
Metallomics. 2018 Oct 25, [epub ahead of print]

Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma
Hoang-Minh, L. B., Siebzehnrubl, F. A., Yang, C., Suzuki-Hatano, S., Dajac, K., Loche, T., Andrews, N., Schmoll Massari, M., Patel, J., Amin, K., Vuong, A., Jimenez-Pascual, A., Kubilis, P., Garrett, T. J., Moneypenny, C., Pacak, C. A., Huang, J., Sayour, E. J., Mitchell, D. A., Sarkisian, M. R., Reynolds, B. A. and Deleyrolle, L. P.
EMBO J. 2018 Dec 3, 37(23).

Diabetic Cardiomyopathy Modelling Using Induced Pluripotent Stem Cell Derived Cardiomyocytes: Recent Advances and Emerging Models
Graneli, C., Hicks, R., Brolen, G., Synnergren, J. and Sartipy, P.
Stem Cell Rev. 2019 Feb, 15(1):13-22.

Resveratrol Preconditioning Induces Genomic and Metabolic Adaptations within the Long-Term Window of Cerebral Ischemic Tolerance Leading to Bioenergetic Efficiency
Khoury, N., Xu, J., Stegelmann, S. D., Jackson, C. W., Koronowski, K. B., Dave, K. R., Young, J. I. and Perez-Pinzon, M. A.
Mol Neurobiol. 2018 Oct 20,  [epub ahead of print]

HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons
Kishinevsky, S., Wang, T., Rodina, A., Chung, S. Y., Xu, C., Philip, J., Taldone, T., Joshi, S., Alpaugh, M. L., Bolaender, A., Gutbier, S., Sandhu, D., Fattahi, F., Zimmer, B., Shah, S. K., Chang, E., Inda, C., Koren, J., 3rd, Saurat, N. G., Leist, M., Gross, S. S., Seshan, V. E., Klein, C., Tomishima, M. J., Erdjument-Bromage, H., Neubert, T. A., Henrickson, R. C., Chiosis, G. and Studer, L.
Nat Commun. 2018 Oct 19, 9(1):4345.

Platelet releasate promotes skeletal myogenesis by increasing muscle stem cell commitment to differentiation and accelerates muscle regeneration following acute injury
Scully, D., Sfyri, P., Verpoorten, S., Papadopoulos, P., Munoz-Turrillas, M. C., Mitchell, R., Aburima, A., Patel, K., Gutierrez, L., Naseem, K. M. and Matsakas, A.
Acta Physiol (Oxf). 2019 Mar 1, 225(3):e13207.

Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes
Jones, J. R., Kong, L., Hanna, M. G. t., Hoffman, B., Krencik, R., Bradley, R., Hagemann, T., Choi, J., Doers, M., Dubovis, M., Sherafat, M. A., Bhattacharyya, A., Kendziorski, C., Audhya, A., Messing, A. and Zhang, S. C.
Cell Rep. 2018 Oct 23, 25(4):947-958 e4.

Ex vivo human HSC expansion requires coordination of cellular reprogramming with mitochondrial remodeling and p53 activation
Papa, L., Zimran, E., Djedaini, M., Ge, Y., Ozbek, U., Sebra, R., Sealfon, S. C. and Hoffman, R.
Blood Adv. 2018 Oct 23, 2(20):2766-2779.

Mitochondrial oxidation of the carbohydrate fuel is required for neural precursor/stem cell function and postnatal cerebellar development
Zheng, H., Yu, W. M., Shen, J., Kang, S., Hambardzumyan, D., Li, J. Y., Shen, Y., Kenney, A. M., Chen, J. and Qu, C. K.
Sci Adv. 2018 Oct 10, 4(10):eaat2681.

Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells
Stone, O. A., El-Brolosy, M., Wilhelm, K., Liu, X., Romao, A. M., Grillo, E., Lai, J. K. H., Gunther, S., Jeratsch, S., Kuenne, C., Lee, I. C., Braun, T., Santoro, M. M., Locasale, J. W., Potente, M. and Stainier, D. Y. R.
Nat Commun. 2018 Oct 9, 9(1):4077.

Techniques & Methods

Real-Time Imaging of Mitochondrial ATP Dynamics Reveals the Metabolic Setting of Single Cells
Depaoli, M. R., Karsten, F., Madreiter-Sokolowski, C. T., Klec, C., Gottschalk, B., Bischof, H., Eroglu, E., Waldeck-Weiermair, M., Simmen, T., Graier, W. F. and Malli, R.
Cell Rep. 2018 Oct 9, 25(2):501-512 e3.

Methods in Molecular Biology - Metabolic Signaling 2019
Fendt, S. M. and Lunt​, S. Y.
Springer International Publishing. 2019 Jan 1, [epub ahead of print]

Shock Wave Therapy Enhances Mitochondrial Delivery into Target Cells and Protects against Acute Respiratory Distress Syndrome
Lin, K. C., Wallace, C. G., Yin, T. C., Sung, P. H., Chen, K. H., Lu, H. I., Chai, H. T., Chen, C. H., Chen, Y. L., Li, Y. C., Shao, P. L., Lee, M. S., Sheu, J. J. and Yip, H. K.
Mediators Inflamm. 2018 Oct 21, 2018:5425346.

A modified method for isolation of human cardiomyocytes to model cardiac diseases
Guo, G. R., Chen, L., Rao, M., Chen, K., Song, J. P. and Hu, S. S.
J Transl Med. 2018 Oct 22, 16(1):288.

Targeting Tumor Microenvironment by Bioreduction-Activated Nanoparticles for Light-Triggered Virotherapy
Tseng, S. J., Kempson, I. M., Huang, K. Y., Li, H. J., Fa, Y. C., Ho, Y. C., Liao, Z. X. and Yang, P. C.
ACS Nano. 2018 Oct 23, 12(10):9894-9902.

How Supraphysiological Oxygen Levels in Standard Cell Culture Affect Oxygen-Consuming Reactions
Stuart, J. A., Fonseca, J., Moradi, F., Cunningham, C., Seliman, B., Worsfold, C. R., Dolan, S., Abando, J. and Maddalena, L. A.
Oxid Med Cell Longev. 2018 Sep 30, 2018:8238459.

Toxicology Research

Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury
Longo, D. M., Woodhead, J. L., Walker, P., Heredi-Szabo, K., Mogyorosi, K., Wolenski, F. S., Dragan, Y. P., Mosedale, M., Siler, S. Q., Watkins, P. B. and Howell, B. A.
Toxicol Sci. 2019 Feb 1, 167(2):458-467.

Biological impacts of organophosphates chlorpyrifos and diazinon on development, mitochondrial bioenergetics, and locomotor activity in zebrafish (Danio rerio)
Cao, F., Souders, C. L., 2nd, Li, P., Pang, S., Qiu, L. and Martyniuk, C. J.
Neurotoxicol Teratol. 2018 Oct 2, [epub ahead of print]

Impact of in vitro heavy metal exposure on pancreatic beta-cell function
Dover, E. N., Patel, N. Y. and Styblo, M.
Toxicol Lett. 2018 Dec 15, 299(137-144.

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis
Soberanes, S., Misharin, A. V., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., Chen, C. I., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Antalek, M., Abdala-Valencia, H., Chiarella, S. E., Sun, K. A., Woods, P. S., Ghio, A. J., Jain, M., Perlman, H., Ridge, K. M., Morimoto, R. I., Sznajder, J. I., Balch, W. E., Bhorade, S. M., Bharat, A., Prakriya, M., Chandel, N. S., Mutlu, G. M. and Budinger, G. R. S.
Cell Metab. 2019 Feb 5, 29(2):335-347 e5.

Reduction of Cisplatin-Induced Ototoxicity without Compromising Its Antitumor Activity
Surnar, B., Kolishetti, N., Basu, U., Ahmad, A., Goka, E., Marples, B., Kolb, D., Lippman, M. E. and Dhar, S.
Biochemistry. 2018 Nov 20, 57(46):6500-6513.

Translational Research

Bi-allelic mutations of LONP1 encoding the mitochondrial LonP1 protease cause pyruvate dehydrogenase deficiency and profound neurodegeneration with progressive cerebellar atrophy
Nimmo, G. A. M., Venkatesh, S., Pandey, A. K., Marshall, C. R., Hazrati, L. N., Blaser, S., Ahmed, S., Cameron, J., Singh, K., Ray, P. N., Suzuki, C. K. and Yoon, G.
Hum Mol Genet. 2019 Jan 15, 28(2):290-306.

Intracellular cholesterol accumulation and coenzyme Q10 deficiency in Familial Hypercholesterolemia
Suarez-Rivero, J. M., de la Mata, M., Pavon, A. D., Villanueva-Paz, M., Povea-Cabello, S., Cotan, D., Alvarez-Cordoba, M., Villalon-Garcia, I., Ybot-Gonzalez, P., Salas, J. J., Muniz, O., Cordero, M. D. and Sanchez-Alcazar, J. A.
Biochim Biophys Acta Mol Basis Dis. 2018 Dec 1, 1864(12):3697-3713.

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